BLAD ß-Lactamase Database
A comprehensive database of widely circulated ß-Lactamases
Welcome to ß-Lactamase
Beta-lactamases are enzymes  produced by some bacteria and are responsible for their resistance to beta-lactam antibiotics like penicillins, cephamycins, and carbapenems (ertapenem) (Cephalosporins are relatively resistant to beta-lactamase). These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam.
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Betalactam antibiotics and inhibitors inhibit the growth of sensitive bacteria by inactivating enzymes. Beta-lactams inhibit not just a single enzyme involved in cell wall synthesis, but a family of related enzymes aspects of cell wall synthesis. These enzymes can be detected by their covalent binding of radioactively-labeled penicillin or other  beta-lactams
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Interdisciplinary Biotechnology Unit
Aligarh Muslim University, Aligarh-202001
Uttar Pradesh, India
http://www.drasadlab.in
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